An older commentary on Acts that I own points out the following interesting facets of Damascus in Christianity and Islam:
“In the history of religion,” writes Dr. G.A. Smith, “Damascus was the stage of two great crises. She was the scene of the conversion of the first Apostle of Christianity to the Gentiles; she was the first Christian city to be taken by Islam.”
If Damascus was not the oldest, it may at all events be called the most enduring city in the world. According to Josephus, Ant. 1.6, 4 it was founded by Uz, the grandson of Shem, whilst a Moslem tradition makes Eliezer its founder, and Abraham its king (see also Jos., Ant., i.7, 2), Here, too, was the traditional scene of the murder of Abel (Shakespeare, I King Henry VI., i,, 3).
The passage referred to in Shakespeare is:
Nay, stand thou back, I will not budge a foot:
This be Damascus, be thou cursed Cain,
To slay thy brother Abel, if thou wilt.